NEUTROPHIL LYMPHOCYTES RATIO AS A PREDICTOR OF BACTEREMIA IN CHILDREN

Nurhasanah Lubis, Bugis Mardina Lubis, Syahril Pasaribu, Ayodhia Pitaloka Pasaribu

Abstract


Bacterial infections are an important problem in the world. Early and accurate diagnosis to detect
infection is very important in order to reduce mortality. Many bacterial infections that cause leukocytes
are circulating and are characterized by increased neutrophils and decreased lymphocytes, this is caused by the inammatory
process. The neutrophil lymphocyte ratio (NLR) is one of the infection markers currently being investigated because it is easy to
do, simple with relatively low cost so that it can be used in daily practice. Research with a cross-sectional retrospective design on
children performed blood culture at H. Adam Malik Hospital in 2017. Sampling was done in total population and a sample of 506
children who met the inclusion and exclusion criteria was obtained. Data analysis used the chai squared test (p <0.05). This
study looked at the 5 most bacteria, namely Klebsiella pneumonia, Acinetobacter baumanii, Staphylococcus aureus,
Escherichia coli, Staphylococcus haemolyticus. The neutrophil lymphocyte ratio is better for determining bacteremia with
sensitivity of 80.5%, specicity of 26.9%, positive predictive value of 33% and negative predictive value of 74% and cut off 1.3 but
cannot be used as a guide because the relationship between blood culture and NLR is not signicant with (p=0.1) and (OR=1.4)


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