RANDOMISED CONTROLLED STUDY TO EVALUATE THE EFFECTS OF NITROGLYCERINE SUBLINGUAL SPRAY ON TRACHEAL EXTUBATION RESPONSE IN NORMOTENSIVE PATIENTS UNDERGOING SURGERIES UNDER GENERAL ANAESTHESIA

Dr Surendra Kumar Raikwar, Dr Anil Kori, Dr Aditya Agarwal

Abstract


Tracheal extubation is the translaryngeal removal of a tube from the trachea via the nose or mouth and associated with awakening, pain, anxiety,
airway irritation which may cause a cough or difculties in breathing and may contribute to an increase in haemodynamic response (1) .Several
modalities, both pharmacological and nonpharmacological have been tried to decrease this stress response with variable success. We undertook
this study to assess the efcacy of NTG spray in decreasing extubation related stress response in normotensive patients undergoing elective
surgeries under general anaesthesia.
Material and methods : Sixty normotensive patients were included in study and randomly subdivided into two groups of 30 patients each – group
N receiving NTG spray and Group C not receiving NTG spray prior to extubation. Hemodynamic stress response during extubation was noted in
both the groups and compared.
Result and conclusion : Extubation was associated with signicant rise in systolic, diastolic and mean arterial blood pressure and heart rate in both
the groups, but this stress response was signicantly less in NTG Group as compared to control group.


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