EOSINOPHILIC ESOPHAGITIS AND EOSINOPHILIC GASTROENTERITIS- NOT SO RARE?

Dr Suryawanshi Neha R, Dr Redewad Nagnath K, Dr Pawar Sunil V, Dr Mahajani Sheetal, Dr Thorat Vinay K, Dr Sangle Shashikala A

Abstract


Eosinophilic gastro-intestinal disorder is an uncommon disorder presenting with non-specic gastrointestinal symptoms. It is diagnosed by
demonstrating eosinophilic inltration of gut wall after excluding other causes of eosinophilia. It is likely a hypersensitivity response to food
allergen. The most common symptoms of patients are abdominal pain, nausea, vomiting, early satiety, and diarrhoea. It responds well to
corticosteroids. We hereby present two cases – eosinophilic esophagitis and eosinophilic duodenitis- seen in a span of one month, presenting with
vague gastro-intestinal symptoms for over a year. Their endoscopic biopsy showed eosinophilic inltration of mucosa. The aim of presenting the
cases is to increase awareness of this disorder as high index of suspicion is necessary to diagnose these patients.


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References


Talley NJ, Shorter RG, Phillips SF, Zinsmeister AR. Eosinophilic gastroenteritis: a clinicopathological study of patients with disease of the mucosa, muscle layer, and subserosal tissues. Gut 1990; 31:54.

A. Mori, C. Enweluzo, D. Grier, and M. Badireddy, “Eosinophilic gastroenteritis: review of a rare and treatable disease of the gastrointestinal tract,” Case Reports in Gastroenterology, vol. 7, no. 2, pp. 293–298, 2013. View at Publisher • View at Google Scholar • View at Scopus

G. P. de Chambrun, F. Gonzalez, J.-Y. Canva et al., “Natural history of eosinophilic gastroenteritis,” Clinical Gastroenterology and Hepatology, vol. 9, no. 11, pp. 950–956.e1, 2011. View at Publisher • View at Google Scholar • View at Scopus

Yun MY, Cho YU, Park IS, et al. Eosinophilic gastroenteritis presenting as small bowel obstruction: a case report and review of the literature. World J Gastroenterol 2007; 13:1758.

Caldwell JH, Tennenbaum JI, Bronstein HA. Serum IgE in eosinophilic gastroenteritis. Response to intestinal challenge in two cases. N Engl J Med 1975; 292:1388.

Klein NC, Hargrove RL, Sleisenger MH, Jeffries GH. Eosinophilic gastroenteritis. Medicine (Baltimore)1970; 49:299

S. Khan and S. R. Orenstein, “Eosinophilic gastroenteritis,” Gastroenterology Clinics of North America, vol. 37, no. 2, pp. 333–348, 2008. View at Publisher • View at Google Scholar • View at Scopus

Cello JP. Eosinophilic gastroenteritis--a complex disease entity. Am J Med 1979; 67:1097.

Lee CM, Changchien CS, Chen PC, et al. Eosinophilic gastroenteritis: 10 years’ experience. Am J Gastroenterol 1993; 88:70.

Lee M, Hodges WG, Huggins TL, Lee EL. Eosinophilic gastroenteritis. South Med J 1996; 89:189.

Lucendo AJ, Molina-Infante J, Arias Á, et al. Guidelines on eosinophilic esophagitis: evidence-based statements and recommendations for diagnosis and management in children and adults. United European Gastroenterol J. 2017;5(3):335-358.

N. Powell, M. M. Walker, and N. J. Talley, “Gastrointestinal eosinophils in health, disease and functional disorders,” Nature Reviews Gastroenterology and Hepatology, vol. 7, no. 3, pp. 146–156, 2010. View at Publisher • View at Google Scholar • View at Scopus

T. Löscher and E. Saathoff, “Eosinophilia during intestinal infection,” Best Practice and Research: Clinical Gastroenterology, vol. 22, no. 3, pp. 511–536, 2008. View at Publisher • View at Google Scholar • View at Scopus

Spergel JM, Shuker M. Nutritional management of eosinophilic esophagitis. Gastrointest Endosc Clin N Am 2008; 18:179.

Kagalwalla AF, Sentongo TA, Ritz S, et al. Effect of six-food elimination diet on clinical and histologic outcomes in eosinophilic esophagitis. Clin Gastroenterol Hepatol 2006; 4:1097


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