EFFICACY AND SAFETY OF DEFLAZACORT IN THE TREATMENT OF PAEDIATRIC NEPHROTIC SYNDROME

Dr Amar Nath Upadhyay, Dr. Neha Negi, Dr. Anant Narayan Sinha

Abstract


Nephrotic syndrome, an acute renal disorder mostly affects children but may occur in adults also. It is characterized by generalized swelling,
proteinuria, excess albuminuria, low serum albumin and hyperlipidemia. It can be classied as primary, secondary and miscellaneous type.
Corticosteroid is the main drug to treat NS but their side effects are bigger challenges. We elucidate the efcacy and safety of Deazacort in
paediatric NS.


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References


Bagga A, Ali U, Banerjee S, et al. Management of steroid sensitive nephrotic syndrome: Revised guidelines. Indian Pediatr 2008; 45(3): 203-214.

Kakar S, Kumar V, Singh R. Latest research progress on acute nephrotic syndrome. 2017; 6(6):255-259.

Singhal R, Pandit S, Dhawan N. Deflazacort Versus Prednisolone: Randomized Controlled Trial in Treatment of Children With Idiopathic Nephrotic Syndrome. Iran J Pediatr. 2015 Apr; 25(2): e510.

Ghosal SP, Chaudhuri JN. Nephrotic syndrome in children. A survey of 45 cases. The Indian Journal of Pediatrics. 1958, 25:637

Arneil GC. The nephrotic syndrome. Pediatr Clin North Am. 1971 May;18(2):547–559.

S Gulati , V Kher, A Gupta, P Arora, P K Rai, R K Sharma. Spectrum of Infections in Indian Children With Nephrotic Syndrome. Pediatr Nephrol.1995; 9 (4), 431-4

Broyer M, Terzi F, Lehnert A et al. A controlled study of Deflazacortin the treatment of idiopathic nephrotic syndrome. Pediatric Nephrology. 1997; 11(4):418-422


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