Dr.T. Susmitha, Dr.G. Nirmala Vani


The simultaneous or sequential development of autoimmune hemolytic anemia (AIHA) and idiopathic
thrombocytopenic purpura (ITP) is known as Evans syndrome, which is very rare in pregnancy. We experienced a case of
Evans syndrome in pregnancy. A 23-year-old primigravida with 37 weeks of gestation presented to the labor room with
Evans syndrome. Her blood reports revealed features of hemolysis with macrocytic anemia, thrombocytopenia,
elevated LDH, and low serum haptoglobin levels, and a direct antiglobulin test (DAT) was positive. A healthy female
newborn with 3200 g was delivered by cesarean section. After delivery, DAT remained positive, and her platelet count
falls markedly, and bone marrow transplantation was done. When Evans syndrome diagnosed during pregnancy, close
and careful observation is essential because it can worsen both the maternal and fetal condition.

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