A CORRELATIONAL STUDY BETWEEN COUPLING INTERVAL RATIO AND SYMPTOMS IN PATIENTS WITH IDIOPATHIC VENTRICULAR PREMATURE COMPLEXES IN 24 HRS HOLTER MONITORING

Dr. G. Dharmaraj, Dr. G. Ravishankar

Abstract


Background and objective: Ventricular premature complexes (VPCs) are the most common arrhythmia encountered in
cardiology OPD. Patients with frequent VPCs are often symptomatic. Our study aims to identify the ECG predictors of
symptoms in patients with idiopathic VPCs in 24 hours Holter monitoring.
Subjects and methods: This study was conducted on 102 patients with VPCs during the period of February 2019 to
December 2019 in cardiology OPD of our centre. All the patients were screened with transthoracic echocardiography.24
hours Holter monitoring was done, the measured parameters were QRS width (Both in sinus beat & VPC), coupling
interval (CI), CI ratio (CL/sinus cycle length) and VPC burden (Number and percentage of VPCs per day).
Results: Both group had similar categorical age group and gender.ORS width of both sinus beat (P = 0.389) and VPCs (P
= 0.035), VPC CI (P=0.487) and VPC burden (P = 0.458) did not correlate with symptoms but VPC CI ratio were
significantly higher in Group B(symptomatic) than in group A (P = 0.004)
Conclusion: There is a relationship between VPC related symptoms and VPC CI ratio.


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References


Gaita F, Giustetto C, Di Donna, et al. Long-term follow-up of right ventricular monomorphic extrasystoles. J Am Coll Cardiol 2001;38:364-

Conti CR. Ventricular arrhythmias: a general cardiologist’s assessment of therapies in 2005. Clin Cardiol 2005;28:314-6.

Ghanbari H, Schmidt M, Machado C, Daccarett M. Catheter ablation of ventricular tachycardia in structurally normal hearts. Expert Rev Cardiovasc Ther 2010;8:651-61.

Wilber DJ. Ventricular ectopic beats: not so benign. Heart 2009;95: 1209-10.

Baman TS, Lange DC, Ilg KJ, et al. Relationship between burden of premature ventricular complexes and left ventricular function. Heart Rhythm 2010;7:865-9.

Sarrazin JF, Labounty T, Kuhne M, et al. Impact of radiofrequency ablation of frequent post-infarction premature ventricular complexes on left ventricular ejection fraction. Heart Rhythm 2009;6:1543-9.

Yarlagadda RK, Iwai S, Stein KM, et al. Reversal of cardiomyopathy in patients with repetitive monomorphic ventricular ectopy originating from the right ventricular outflow tract. Circulation 2005;112:1092-7.

Bogun F, Crawford T, Reich S, et al. Radiofrequency ablation of frequent, idiopathic premature ventricular complexes: comparison with a control group without intervention. Heart Rhythm 2007;4:863-7.

Takemoto M, Yoshimura H, Ohba Y, et al. Radiofrequency catheter ablation of premature ventricular complexes from right ventricular outflow tract improves left ventricular dilation and clinical status in patients without structural heart disease. J Am Coll Cardiol 2005;45:1259-65.

Oh HL, Choue CW, Cho JM, et al. Clinical characteristics of ventricular premature beats originating from right ventricular outflow tract. Korean Circ J 2003;33:1118-25.

Rolfe SJ, Rasor T, Shaffer PA, Sanitate PA, Bashore TM. Relation between premature ventricular contraction site of origin (defined by radionuclide phase analysis) and subsequent left ventricular function. Am J Cardiol 1984;53:1028-33.

Migliore F, Folino AF, Bilato C, et al. Origin of recurrent syncope in patient with right ventricular outflow tract arrhythmias: evidence of autonomic modulation of the ectopic foci. J Cardiovasc Med 2011;12:598-600.

Chen JY, Tsai WC, Lee YL, et al. Association of premature ventricular complexes with central aortic pressure indices and pulse wave velocity. Am Heart J 2008;155:e1-6.

Huizar JF, Kaszala K, Potfay J, et al. Left ventricular systolic dysfunction induced by ventricular ectopy: a novel model for premature ventricular contraction-induced cardiomyopathy. Circ Arrhythm Electrophysiol 2011;4:543-9.

Ban JE, Lee HS, Lee DI, et al. Electrophysiological characteristics related

to outcome after catheter ablation of idiopathic ventricular arrhythmia originating from the papillary muscle in the left ventricle. Korean Circ J 2013;43:811-8.

Sun Y, Blom NA, Yu Y, et al. The influence of premature ventricular contractions on left ventricular function in asymptomatic children without structural heart disease: an echocardiographic evaluation. Int J Cardiovasc Imaging 2003;19:295-9.

Komatsu T, Ikeda K, Tomoike H. Assessment of the variability in coupling intervals of ventricular premature contractions. Jpn Circ J 1993;57:781-8.

Thanavaro S, Kleiger RE, Miller JP, Province MA, Friedman E, Oliver GC. Coupling interval and types of ventricular ectopic activity associated with ventricular runs. Am Heart J 1983;106:484-91.

Jakopin J, Horvat M, Brucan A, Rode P. The relation of heart rhythm to postextrasystolic potentiation. Bibl Cardiol 1979;164-8.

Otsuji Y, Kisanuki A, Toda H, et al. Influence of left ventricular filling profile during preceding control beats on the occurrence of pulse deficit caused by ventricular premature contractions. Eur Heart J 1993;14:1044-9.

Yellin EL, Kennish A, Yoran C, Laniado S, Buckley NM, Frater RW. The influence of left ventricular filling on postextrasystolic potentiation in the dog heart. Circ Res 1979;44:712-22.

Eber LM, Berkovits BV, Matloff JM, Gorlin R. Dynamic characterization of premature ventricular beats and ventricular tachycardias. Am J Cardiol 1974;33:378-83.

Millar K, Eich RH, Abildskov JA. Relation of variations in activation order to intraventricular pressures during premature beats. Circ Res 1966;19:481-8.

Baman TS, Lange DC, Ilg KJ, et al. Relationship between burden of premature ventricular complexes and left ventricular function. Heart Rhythm 2010;7:865-9.

Sarrazin JF, Labounty T, Kuhne M, et al. Impact of radiofrequency ablation of frequent post-infarction premature ventricular complexes on left ventricular ejection fraction. Heart Rhythm 2009;6:1543-9.

Efremidis M, Letsas KP, Sideris A, Kardaras F. Reversal of premature ventricular complex-induced cardiomyopathy following successful radio-frequency catheter ablation. Europace 2008;10:769-70.

Mountantonakis SE, Frankel DS, Gerstenfeld EP, et al. Reversal of outflow tract ventricular premature depolarization-

induced cardiomyopathy with ablation: effect of residual arrhythmia burden and preexisting cardiomyopathy on outcome.

Heart Rhythm

.Kyoung –Min park, MD et al.Coupling Intrval Ratio is associated with Ventricular Premature Complex related

symptoms.Korean Circ J 2015;45(4)294-300


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